Natural history of cervical intraepithelial neoplasia in pregnancy : postpartum 1 histo - pathologic outcome and review of the literature 2 3 4
نویسندگان
چکیده
4 Mariella Mailath-Pokorny, Richard Schwameis, Christoph Grimm, Alexander Reinthaller, 5 Stephan Polterauer 6 7 8 1. Medical University of Vienna, Department of Obstetrics and Gynecology, 9 Division of Obstetrics and Feto-maternal Medicine 10 11 2. Medical University of Vienna, Comprehensive Cancer Center, Gynecologic Cancer 12 Unit, Department of Obstetrics and Gynecology, 13 Division of General Gynecology and Gynecologic Oncology 14 15 3. Karl Landsteiner Institute for General Gynecology and Experimental Gynecologic 16 Oncology, Austria 17 18 19 Corresponding author: 20 Stephan Polterauer MD 21 Associate Professor, Department of Obstetrics and Gynecology, 22 Medical University Vienna, Waehringer Guertel 18-20, 23 A-1090 Vienna, Austria, TEL: +43 1 4040
منابع مشابه
Natural history of cervical intraepithelial neoplasia in pregnancy: postpartum histo-pathologic outcome and review of the literature
BACKGROUND To study the natural history of cervical intraepithelial neoplasia (CIN) during pregnancy and to compare the rates of persistence, progression and regression of CIN by colposcopically guided biopsy (CGB) during pregnancy with outcome in non-pregnant-women. METHODS A retrospective analysis of all pregnant women diagnosed with CIN at our outpatient clinic between 2005 and 2010 was pe...
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BACKGROUND The incidence of cervical cancer in pregnancy is estimated to be 1-10/10000 pregnancies. Approximately 3% of cervical cancers are diagnosed during pregnancy. The incidence of abnormal Pap smears has been reported to be 5%-8%. Data on the spontaneous evolution of an intraepithelial neoplasia during pregnancy are quite diverse. Of dysplasia cases diagnosed during pregnancy, 10%-70% reg...
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Background: Cervical intraepithelial neoplasia (CIN) is a premalignant lesion capable of progressing to cervical cancer. Despite the existing well-defined criteria, the histomorphologic diagnosis is subject to high rates of discordance among pathologists. The aim of this study was to evaluate Ki-67 (MIB-1), CK17 and p16 INK4a (p16) markers by immunohistochemical methods in differentiating CIN f...
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Background and Objective: To estimate the risk of human papilloma virus (HPV) infection for cervical malignancies, we conducted a case-control study in southern Iran (Hormozgan province). Materials and Methods: For this purpose,52 paraffin embedded blocks with exact diagnosis of cervical carcinoma(50 carcinomas and 2 carcinomas in situ) from 2001 to 2006 and 52 praffin embedded blocks of ce...
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Background and Objective: The currentstudy aimed at investigating the histomorphological spectrum of cervical intraepithelial and invasive lesions assessing the diagnostic significance of P16/INK4a and Ki-67 in such lesions, andcorrelatingP16/INK4a and Ki-67 immunoexpression with histologic type and grade.Methods: A total of 60 cases were selectedcomprisi...
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